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Examples
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Dunne MJ, Shepherd RM, Cosgrove KE, Macfarlane WM, Lindley KJ, James RF, et al. Persistent hyperinsulinaemic hyperglycaemia of infancy-derived cells; implications for beta-cells that replicate in vitro.
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ANTIDIABETES Improving the secretion of insulin by repairing damaged pancreatic beta-cells; promoting the absorption of glucose in the liver; inhibiting the release of glucose from the liver by increasing hexokinase activity; reducing glucose-6-phosphatase activity
Forever Young M.D. Nicholas Perricone 2010
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Also, the fat reserves in our body are known to release various inflammatory hormones and free fatty acids that possibly kill pancreatic insulin secreting beta-cells.
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Pleiotropic effects of fatty acids on pancreatic beta-cells.
Saturated fat study sucks | The Blog of Michael R. Eades, M.D. 2006
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Glucose toxicity in beta-cells: Type 2 diabetes, good radicals gone bad, and the glutathione connection.
Fat is Not Your Fate Susan Mitchell Ph.D. 2005
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Glucose toxicity in beta-cells: Type 2 diabetes, good radicals gone bad, and the glutathione connection.
Fat is Not Your Fate Susan Mitchell Ph.D. 2005
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Stem cells that normally grow into sperm can be prodded to change into insulin-producing beta-cells instead, researchers from the Georgetown University
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That in turn may mean that more of my beta-cells are being killed through the auto-immune attack than necessary, since every time one of the cells "rears its head" (that's how I imagine it) to secrete insulin granules, it faces an attack from the angry (misguided) immune system ...
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I don't think I'm anywhere near levels where glucose toxicity will kill beta-cells but the need for more insulin from overworked cells that are under attack worries me.
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Dr. Melton's group screened over 1,000 transcription factors to find which could make the exocrine cells turn into beta-cells.
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