American Heritage® Dictionary of the English Language, Fourth Edition
- n. A physiological mechanism that alters the permeability of brain capillaries, so that some substances, such as certain drugs, are prevented from entering brain tissue, while other substances are allowed to enter freely.
- n. anatomy A structure in the central nervous system (CNS) that keeps various substances found in the bloodstream out of the brain while allowing in the substances essential to metabolic function, e.g. oxygen.
- n. a mechanism that creates a barrier between brain tissues and circulating blood; serves to protect the central nervous system
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“Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity.”
“The next step in Wakefield’s hypothesis was dependent on a widely discredited “opioid excess” theory of autism, which drew parallels between autistic children and doped-up lab rats: After the opioid peptides that are naturally produced during digestion escaped through the gut’s newly porous walls, Wakefield argued, they breached the blood-brain barrier and overwhelmed developing children’s brains.”
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