Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A multifunctional protein that binds calcium ions

Etymologies

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Examples

  • Illustrated in Figure 7 is the restriction enzyme and genetic map of a commercially available (BD Biosciences Clontech) bacterial plasmid derivative containing the coding sequence for enhanced yellow fluorescent protein fused to the endoplasmic reticulum targeting sequence of calreticulin (a resident protein).

    Archive 2005-10-01

  • Although there are several ER-localized HSPs that can potentially chaperone PRRs, including calnexin, calreticulin, protein disulfide isomerase, gp96, thiol-oxidoreductase ERp57, and BiP, to date only gp96 has been demonstrated to function in PRR-folding

    PLoS ONE Alerts: New Articles

  • In the current study, we explored the combination of the DNA vaccine encoding calreticulin

    BioMed Central - Latest articles

  • Endogenous ER markers ERGIC-53 and calreticulin as well as plasma membrane protein markers Na/K ATPase and Na/Ca exchanger (NCX) were probed against to allow accurate visualization of the ER and the plasma membrane.

    PLoS ONE Alerts: New Articles

  • Now, the new research has shown that calreticulin exists in a variety of cancers, including some types of leukemia, non-Hodgkin's lymphoma and bladder, brain and ovarian cancers.

    Yahoo! News: Business - Opinion

  • "The research also shows that most normal cell populations don't display calreticulin and are, therefore, not depleted when we expose them to a blocking anti-CD47 antibody."

    Yahoo! News: Business - Opinion

  • This research demonstrates that the reason that blocking the CD47 'don't eat me' signal works to kill cancer is that leukemias, lymphomas and many solid tumors also display a calreticulin

    Yahoo! News: Business - Opinion

  • The next step is to understand how calreticulin works.

    Yahoo! News: Business - Opinion

  • A study published online Dec. 22 in Science Translational Medicine reports that the cells send out the enticing "eat me" signal by displaying the protein calreticulin.

    Yahoo! News: Business - Opinion

  • Both the pre-apoptotic exposure of calreticulin (CRT) and the post-apoptotic release of high-mobility group box 1 protein (HMGB1) are required for immunogenic cell death elicited by anthracyclins.

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