from The American Heritage® Dictionary of the English Language, 4th Edition
- n. The dissolution or disintegration of chromophil material, such as chromatin, within a cell.
from The Century Dictionary and Cyclopedia
- n. Dissolution of the nuclear chromatin: an evidence of coagulation necrosis on the part of cells.
Sorry, no etymologies found.
Somewhat later a change, termed chromatolysis, takes place in the nerve cells, and consists of a breaking down and an ultimate disappearance of the Nissl bodies.
These granules disappear (chromatolysis) during fatigue or after prolonged stimulation of the nerve fibers connected with the cells.
The injection of adrenalin causes striking brain-cell changes: first, a hyperchromatism, then a chromatolysis.
B: Section of Cerebellum of Dog Showing the Effect of the Brain-cells of Iodoform Poisoning (x310). a increased mental tone; while the brain-cells accurately display these physiologic alterations in proportional hyperchromatism in the active stages, and proportional chromatolysis in the stages of reaction.
Animals upon whom double adrenalectomy has been performed show a striking fall in temperature, muscular weakness, -- after adrenalectomy the animal may not be able to stand even, -- and progressive chromatolysis.
Adrenalin alone causes hyperchromatism followed by chromatolysis, and in overdosage causes the destruction of some brain-cells.
In brief, the agencies that in our brain-cell studies were found to cause hyperchromatism followed by chromatolysis gave positive results in the Cannon test for adrenalin (Fig. 62).
If the axis cylinder is severed at any point, it degenerates beyond that point, and the nucleus of the nerve-cell disintegrates -- chromatolysis.
We have found, on microscopic examination in such cases, in addition to these small extravasations, collections of colloid bodies, patches of miliary sclerosis, and chromatolysis and vacuolation of nerve-cells. [
Wordnik is becoming a not-for-profit! Read our announcement here.