Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics Any protein that binds to an activator as part of gene transcription

Etymologies

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Examples

  • In contrast, FGF-19 increased the activity of STAT3, an inhibitor of SREBP-1c expression and decreased the expression coactivator-1β (PGC-1β), an activator of SREBP-1c activity.

    Journal of Biological Chemistry current issue 2009

  • When mice that lack steroid receptor-2 (SRC-2) - a master regulator gene called a coactivator

    Health News from Medical News Today 2008

  • Like, what regulates the SRC-3 coactivator, plus two other ones?

    A Dubious "Opportunity" for IDers 2007

  • Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.

    Fat is Not Your Fate Susan Mitchell Ph.D. 2005

  • Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.

    Fat is Not Your Fate Susan Mitchell Ph.D. 2005

  • "At the membrane, the enzyme PAK1 (p21-activted kinase 1) phosphorylates (attaches a phosphate molecule that activates the coactivator) SRC-3, allowing it to function at the membrane," said O'Malley, responsible for identifying the first receptor coactivator and advancing the field in general.

    THE MEDICAL NEWS Editors 2010

  • "At the membrane, the enzyme PAK1 (p21-activted kinase 1) phosphorylates (attaches a phosphate molecule that activates the coactivator) SRC-3, allowing it to function at the membrane," said O'Malley, responsible for identifying the first receptor coactivator and advancing the field in general.

    THE MEDICAL NEWS Editors 2010

  • "At the membrane, the enzyme PAK1 (p21-activted kinase 1) phosphorylates (attaches a phosphate molecule that activates the coactivator) SRC-3, allowing it to function at the membrane," said O'Malley, responsible for identifying the first receptor coactivator and advancing the field in general.

    THE MEDICAL NEWS Editors 2010

  • Zhu Y, Qi C, Cao WQ, Yeldandi AV, Rao MS, et al. (2001) Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function.

    PLoS ONE Alerts: New Articles Anil K. Singh et al. 2010

  • "At the membrane, the enzyme PAK1 (p21-activted kinase 1) phosphorylates (attaches a phosphate molecule that activates the coactivator) SRC-3, allowing it to function at the membrane," said O'Malley, responsible for identifying the first receptor coactivator and advancing the field in general.

    RedOrbit News - Technology 2010

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