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  1. costimulatory love

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Definitions

Wiktionary

  1. adj. Of or pertaining to co-stimulation

Examples

  • “Ongoing studies involve the role of chemokine-dependent pathways in graft rejection and tolerance; identification and characterization of costimulatory pathways; manipulation of the NFkB pathway; and development of practical tools to enhance the function of regulatory T cells, so as to improve outcomes post-transplant; further details are available.”

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  • “Relative normalized transcript expression of costimulatory genes in human clinical blood samples.”

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  • “+ DC expressed costimulatory surface markers CD80 (65. 66% vs. 17. 43%), CD86 (57. 43% vs. 30%) and CD40 (44% vs. 35%) compared with iCD8”

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  • “Pelfrey CM, Moldovan IR, Cotleur AC, Zamor N, Rudick RA (2005) Effects of sex hormones on costimulatory molecule expression in multiple sclerosis.”

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  • “The randomized phase II study involved the PROSTVAC-VF vaccine, a combination of two weakened poxviruses that have been genetically programmed to produce slightly irregular versions of prostate specific antigen (PSA) - a protein on the surface of prostate cells that is abnormal in many prostate cancers - and three costimulatory molecules that spur the immune system to a more vigorous attack on tumor cells.”

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  • “The randomized phase II study involved the PROSTVAC-VF vaccine, a combination of two weakened poxviruses that have been genetically programmed to produce slightly irregular versions of prostate specific antigen (PSA) a protein on the surface of prostate cells that is abnormal in many prostate cancers and three costimulatory molecules that spur the immune system to a more vigorous attack on tumor cells.”

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  • “We have previously shown that geranylgeranyl transferase inhibition (done with GGTI-298) stimulates anti-melanoma immune response through MHC-I and costimulatory molecule expression in the B16F10 murine model In this study, it is shown that vaccination with mIFN-gand GGTI-298 pretreated B16F10 cells induces a protection against untreated tumor growth and pulmonary metastases implantation.”

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  • “Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens (MHC-I) and costimulatory molecules.”

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  • “Toulouse, France Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens (MHC-I) and costimulatory molecules.”

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  • “There are two families of costimulatory molecules expressed in antigen presenting cells (APCs) and some tumor cells: B7 and TNF/TNF receptor (TNF-R).”

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‘costimulatory’ has been looked up 872 times, loved by 1 person, and is not a valid Scrabble word.