- n. biochemistry An integral membrane protein that actively transports molecules by using the concentration gradient of one molecule or ion concentration to force the other molecule or ion against its gradient
- cotransport + -er (Wiktionary)
“Dear Egon, maybe I'm a little bit late with my comment, but dapagliflozin is not a DPP-4 inhibitor but a sodium glucose cotransporter type 2 SGLT-2 inhibitor.”
“Genetic analysis revealed a homozygous in-frame duplication of 21 bp in SLC34A1, which encodes the renal sodium-inorganic phosphate cotransporter NaPi-IIa, as the causative mutation.”
“Lexicon's dual sodium-glucose cotransporter 2 (SGLT2) and SGLT1 inhibitor, type 2 diabetes were presented at the American Diabetes Association and the Endocrine Society annual meetings in June.”
“LX4211 was developed at Lexicon as a potent inhibitor of the sodium glucose cotransporter 2”
“Forbush B (2003) PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1).”
“Golbang AP, Cope G, Hamad A, Murthy M, Liu CH, et al. (2006) Regulation of the Expression of the Na / Cl cotransporter (NCCT) by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved.”
“Wasserman SM, Anderson KR, Cai J, Falb D, et al. (1997) Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium.”
“+-K+-2Cl − cotransporter 1 (NKCC1), which has an important role in inflammation”
“England R, Delpire E (2006) Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.”
“The neuron-specific K-Cl cotransporter KCC2 maintains the low intracellular chloride concentration required for the fast hyperpolarizing actions of inhibitory neurotransmitters.”
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