Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun 5-aza-2'-deoxycytidine, a cytosine analogue that hypomethylates DNA by inhibiting DNA methyltransferase.

Etymologies

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Examples

  • Dacogen, generically known as decitabine, is meant to treat the ailment in patients 65 years and older for whom chemotherapy has not worked.

    Yahoo! News: Business - Opinion 2012

  • January 13th, 2010 WASHINGTON - An international team of researchers has revealed that a drug called decitabine might help older patients with acute myeloid leukemia (AML).

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 2010

  • Washington, Jan 13: An international team of researchers has revealed that a drug called decitabine might help older patients with acute myeloid leukemia

    dailyindia.com News Feed 2010

  • January 13th, 2010 WASHINGTON - An international team of researchers has revealed that a drug called decitabine might help older patients with acute myeloid leukemia (AML).

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 2010

  • January 13th, 2010 WASHINGTON - An international team of researchers has revealed that a drug called decitabine might help older patients with acute myeloid leukemia (AML).

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 2010

  • In the multicenter, Phase 1/2 clinical trial examining the safety and effectiveness of oral sapacitabine administered sequentially with decitabine, 30-day mortality from all causes was 4.5% and 60-day mortality from all causes was 9.5%.

    unknown title 2011

  • "We are encouraged by the data presented at the 2011 ASCO meeting from a pilot study evaluating sapacitabine dosed sequentially with decitabine, a treatment regimen that mirrors the lead-in arm of our on-going Phase 3 SEAMLESS study," said Spiro Rombotis, President and Chief Executive Officer of Cyclacel.

    unknown title 2011

  • Reported results at the 2011 ASCO meeting from a pilot study evaluating the same treatment regimen of sapacitabine dosed sequentially with decitabine, as one of the arms in SEAMLESS, the registration-directed, Phase 3 study of sapacitabine in elderly patients with newly diagnosed acute myeloid leukemia.

    unknown title 2011

  • Dacogen (decitabine) for Injection is indicated for treatment of patients with myelodysplastic syndromes (MDS), including previously treated and untreated, de novo and secondary MDS of all French-American-British (FAB) subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, chronic myelomonocytic leukemia), and Intermediate-1,

    FinanzNachrichten.de: Aktuelle Nachrichten 2010

  • SuperGen, Inc. (Nasdaq: SUPG), a pharmaceutical company dedicated to the discovery and development of novel cancer therapies, announced that Eisai Inc. today released information regarding a randomized Phase III clinical trial of Dacogen® (decitabine) for Injection in elderly patients with acute myeloid leukemia (AML).

    FinanzNachrichten.de: Aktuelle Nachrichten 2010

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