Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. 5-aza-2'-deoxycytidine, a cytosine analogue that hypomethylates DNA by inhibiting DNA methyltransferase.

Etymologies

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Examples

  • Dacogen, generically known as decitabine, is meant to treat the ailment in patients 65 years and older for whom chemotherapy has not worked.

    Yahoo! News: Business - Opinion

  • January 13th, 2010 WASHINGTON - An international team of researchers has revealed that a drug called decitabine might help older patients with acute myeloid leukemia (AML).

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7

  • Washington, Jan 13: An international team of researchers has revealed that a drug called decitabine might help older patients with acute myeloid leukemia

    dailyindia.com News Feed

  • "We are encouraged by the data presented at the 2011 ASCO meeting from a pilot study evaluating sapacitabine dosed sequentially with decitabine, a treatment regimen that mirrors the lead-in arm of our on-going Phase 3 SEAMLESS study," said Spiro Rombotis, President and Chief Executive Officer of Cyclacel.

  • Reported results at the 2011 ASCO meeting from a pilot study evaluating the same treatment regimen of sapacitabine dosed sequentially with decitabine, as one of the arms in SEAMLESS, the registration-directed, Phase 3 study of sapacitabine in elderly patients with newly diagnosed acute myeloid leukemia.

  • In the multicenter, Phase 1/2 clinical trial examining the safety and effectiveness of oral sapacitabine administered sequentially with decitabine, 30-day mortality from all causes was 4.5% and 60-day mortality from all causes was 9.5%.

  • Dacogen (decitabine) for Injection is indicated for treatment of patients with myelodysplastic syndromes (MDS), including previously treated and untreated, de novo and secondary MDS of all French-American-British (FAB) subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, chronic myelomonocytic leukemia), and Intermediate-1,

    FinanzNachrichten.de: Aktuelle Nachrichten

  • SuperGen, Inc. (Nasdaq: SUPG), a pharmaceutical company dedicated to the discovery and development of novel cancer therapies, announced that Eisai Inc. today released information regarding a randomized Phase III clinical trial of DacogenĀ® (decitabine) for Injection in elderly patients with acute myeloid leukemia (AML).

    FinanzNachrichten.de: Aktuelle Nachrichten

  • Dacogen (decitabine) for Injection is indicated for treatment of patients with myelodysplastic syndromes (MDS), including previously treated and untreated, de novo and secondary MDS of all French-American-British (FAB) subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, chronic myelomonocytic leukemia), and

    The Earth Times Online Newspaper

  • SGI-110, a next-generation decitabine product was referenced by Standup to Cancer funded researchers as an exciting compound that will be the subject of a clinical trial later this year.

    SeekingAlpha.com: Home Page

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