dehalogenation love

Definitions

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  • noun chemistry Any reaction that removes halogen (usually a pair of atoms) from a molecule

Etymologies

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Examples

  • Listed are several of the reducing reactions. azo reduction dehalogenation disulfide reduction nitro reduction

    Biotransformation 2008

  • Atkins, W.M.: Luciferase-dependent, cytochrome P-450-cata - lyzed dehalogenation in genetically engeneered Pseudomonas.

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  • References [1] Schenk, T.; Muller, R.; Mörsberger, F.; Otto, M.K.; Lingens, F.: Enzymatic dehalogenation of pentachlorophenol by extracts from Arthrobacter sp. strain ATCC 33790.

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  • 1.14.13.50 Pentachlorophenol monooxygenase 3 Reaction and Specificity Catalyzed reaction pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride (some tetrachlorophenols and trichlorophenols can act as substrates; mechanism [2]) Reaction type dehalogenation oxidation redox reaction reduction Natural substrates and products S pentachlorophenol + NADPH + O2

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  • 171, 5487-5491 (1989) [2] Schenk, T.; Muller, R.; Lingens, F.: Mechanism of enzymatic dehalogenation of pentachlorophenol by Arthrobacter sp. strain ATCC 33790.

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  • Enzyme appears to lack ab - solute regioselectivty [7]) Reaction type decarboxylation dehalogenation hydroxylation oxidation redox reaction reduction Natural substrates and products S 2,5-dichlorobenzoate + NADH + O2

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