from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A sugar, C5H10O4, that is a constituent of DNA.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A derivative of the pentose sugar ribose in which the 2' hydroxyl (-OH) is reduced to a hydrogen (H); it is a constituent of the nucleotides that comprise the biopolymer, deoxyribonucleic acid, or DNA.
from the GNU version of the Collaborative International Dictionary of English
- n. a pentose (C5H10O4) in which one of the hydroxyl groups of ribose has been replaced by a hydrogen. In deoxyribonucleic acids, the deoxyribose is D-2-deoxyribose, in which the hydroxyl at the 2 position of ribose is the one which is replaced by hydrogen.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a sugar that is a constituent of nucleic acids
Although U-14C cytidine did not label the deoxyribose of E. coli DNA, I found the deoxycytidine of DNA of rat organs to be almost uniformly labeled.
Components of the primary genetic material in our cells, called deoxyribose nucleic acid
Nucleotides consist of a sugar molecule, like ribose or deoxyribose, joined to a base at one end and a phosphate group at the other.
For example, deoxyribose is part of DNA (the genetic material of chromosomes) and ribose is part of RNA (which regulates protein synthesis).
The sugar in DNA is deoxyribose while the bases are adenine, guanine, cytosine and thymine.
Therefore by both criteria it appeared certain that the 14C reached the deoxyribose directly from the cytidine.
The opening sentence of his paper, written with his colleague Jim Watson and published in Nature that year, put it more modestly: "We wish to suggest a structure for the salt of deoxyribose nucleic acid."
Five-carbon sugars are especially important to all life because two of them, ribose and deoxyribose, form the backbones of ribonucleic acid (RNA) and deoxyribonucleic acid (DNA), the carriers of the genetic code.
In 1944 Oswald Avery, Colin, MacLeod and Maclyn McCarthy of Rockefeller University determined that DNA (deoxyribose nucleic acid) carried the hereditary blueprint.
Nucleosides are then formed by the addition of sugar moieties (deoxyribose or ribose) and subsequently converted into nucleotides by the addition of phosphate (mono -, di - and triphosphate).
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