depalmitoylation love

depalmitoylation

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The removal of palmitate esters bound to a protein

Etymologies

Sorry, no etymologies found.

Examples

  • The inhibitor, palmostatin B, perturbs the cellular acylation cycle at the level of depalmitoylation and thereby causes a loss of the precise steady-state localization of palmitoylated Ras.

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  • Cycles of depalmitoylation and repalmitoylation critically control the steady-state localization and function of various peripheral membrane proteins, such as Ras proto-oncogene products.

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  • Figure 2: Palmostatin B specifically inhibits depalmitoylation.

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  • In first half of 2009 Santaris Pharma and academic partners published an article titled: A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis.

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