diazoxide

Definitions

noun A potassium channel activator which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions, used as a vasodilator to treat hypertension and in diabetes to decrease the secretion of insulin.

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Agents such as diazoxide may prolong or deepen subsequent hypotension.

Clonidine Overdose in Children 2010
Diffuse KATP HI usually cannot be controlled with diazoxide medication.

What is HI? 2010
This includes information such as when the low blood sugars started, the timing of the low blood sugar and whether the hypoglycemia responds to diazoxide.

Diagnosis 2010
GDH-HI is typically well controlled with diazoxide.

What is HI? 2010
Most children, who start on diazoxide and in whom it works very well, will be on it for many years.

Diazoxide 2010
However, these gene defects act in a dominant fashion and are usually responsive to medical treatment with diazoxide.

What is HI? 2010
Some patients respond to diazoxide while others may require additional treatment.

What is HI? 2010
Focal KATP HI usually cannot be controlled with diazoxide medication The treatment of focal KATP HI usually includes octreotide, continuous dextrose, and/or pancreatectomy.

What is HI? 2010
In some types of HI, diazoxide works well, in others it is ineffective.

Treatment 2010
Currently available treatments include dietary modification, diazoxide, and, in patients with resistant disease, the use of intravenous dextrose infusion or enteral feedings.

Medlogs - Recent stories 2009