Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A highly active glycoside, C41H64O13, derived from digitalis and prescribed in the treatment of certain cardiac conditions.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A toxic cardiac glycoside, obtained from digitalis, related to cardenolide

from the GNU version of the Collaborative International Dictionary of English

  • n. A steroid glycoside, one of the cardiotonic chemical substances which is extracted from the foxglove. It is a white, crystalline substance (C41H64O13), and is a 3-substituted triglucoside of a steroid, related structurally to digitalin and digoxin. It is used as a cardiotonic for treatment of certain heart conditions, such as congestive heart failure. Chemically it is (3β,5β)-3-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-card-20(22)-enolide. The related compounds digitalin and digoxin are also extracted from the foxglove (Digitalis lanata and Digitalis purpurea). The class of steroid glycosides having cardiotonic properties are refered to as the cardiac glycoside group.

from The Century Dictionary and Cyclopedia

  • n. A poisonous principle obtained from Digitalis in the form of yellowish crystals soluble in alcohol.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. digitalis preparation used to treat congestive heart failure or cardiac arrhythmia

Etymologies

digi(talis) + toxin.
(American Heritage® Dictionary of the English Language, Fourth Edition)

Examples

  • A related chemical, called digitoxin, has been used for decades as a

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  • So it was too slow for digitoxin, and too quick for digoxin.

    Dreaming of the Bones

  • In the vaughan williams of antiarrhythmics, digitoxin is disseminated to start a class ia short {01}.

    Wii-volution

  • The leaves of the oriental foxglove plant contain digitoxin, a drug used to treat heart disease.

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  • Both digoxin, which does not occur in nature and digitoxin can be synthesized, but digoxin's half-life allows once-daily dosing.

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  • The synthetic version of digitoxin has little digestive side effects, while the side effects go directly to the heart, thereby creating much more danger than the herb.

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  • Indeed, many species of vascular plants have for long supplied us with excellent drugs such as morphine from papaver somniferum (used as a pain killer), digitoxin and digoxin from Digitalis lanatan and D. purpurea (for treating congestive heart failures), quinine from Cinchona spp. (for malaria), ergotamine (for migraine headache), from Claviceps purpurea and vincristine from Vinca rosea (for treating leukaemia in children).

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  • If it wasn’t digitoxin, it must have been digoxin.

    Dreaming of the Bones

  • Nor can we even be certain that Lydia Brooke actually died from an overdose of her own medication, even though digoxin was present in her body, because—as I understand it, and I’m no chemist—digoxin is one of the metabolic by-products of digitoxin.

    Dreaming of the Bones

  • And it can’t have been foxglove—the digitoxin in it acts too quickly.

    Dreaming of the Bones

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