from The American Heritage® Dictionary of the English Language, 4th Edition
- n.pl. A rough, dry, scaly condition of the hands typically caused by sensitivity to or excessive use of household detergents or cleaning agents.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Hands which are rough, reddish, and dry, as from irritation and chafing caused by immersion in hot water mixed with detergent.
Possibly coined circa mid-1920s for the advertising of Lever Brothers "Lux" brand dishwashing soap. (Wiktionary)