dose-ranging

This study is a Phase 2b, multicenter, randomized, double-blind, placebo-controlled, dose-ranging, efficacy and safety study, designed to document the clinical benefit of PTC124 when administered as therapy of patients with DMD/BMD due to a nonsense mutation (premature stop codon) in the dystrophin gene.

Neuromuscular Disorder Research Studies, Clinical Trials 2010

It was primarily designed as a dose-ranging study to look at the drug's safety and determine which doses would move into advanced clinical, or phase 3, testing.

Antiblood-Clot Pill Could Cut Heart Problems, Study Says 2008

If successful, this current exploratory clinical study will enable us to better design the protocol and endpoints for a dose-ranging phase 2 trial in a substantially larger number of dry age-related macular degeneration dry AMD patients to determine if unoprostone isopropyl has potential as a treatment for dry AMD.

unknown title 2011

In July 2011, Alkermes announced the initiation of a dose-ranging phase 2b study of ALKS 37 for the treatment of OIC.

unknown title 2011

The companies also presented data from two phase IIb dose-ranging studies which compared fixed-dose combinations of aclidinium bromide + formoterol with aclidinium bromide alone, formoterol alone and placebo.

Forest's COPD Candidate Delivers - Yahoo! Finance 2011

The Phase 2 study was a randomized, double-blind, placebo-controlled, dose-ranging, safety and efficacy study in approximately 353 patients with mild to moderate Alzheimer's disease baseline scores of 16-26 in the Mini-Mental State Examination - MMSE.

unknown title 2011

The results of this phase 2b study, along with those from the dose-ranging, four-week phase 2b study initiated earlier this year, are expected to be part of the End-of-Phase 2 submission package to the U.S. Food and Drug Administration FDA.

unknown title 2011

Basilea has completed the double-blind, randomized, placebo-controlled dose-ranging study in healthy volunteers assessing the pharmacokinetics, safety and tolerability of BAL30072 after multiple ascending doses of intravenous infusions.

Reuters: Press Release 2011

The company is positioned to initiate a dose-ranging Phase 1/2 clinical trial in late 2011 or early 2012 to evaluate the safety and efficacy of ISV-101 when administered to patients suffering from dry eye disease.

unknown title 2011

Prior to initiating the Phase 2 clinical trial, PolyMedix completed three successful Phase 1B/2 trials --- a single dose trial to reverse heparin, a single dose trial to reverse LMWH, and a dose-ranging trial to reverse heparin.

unknown title 2011