- From dys- + synchrony. (Wiktionary)
“The prevalence of intra-ventricular dyssynchrony is high in patients with heart failure, wide QRS and depressed systolic function.”
“Intra-ventricular (regional) dyssynchrony in a 16-segment model was expressed either as a delayed longitudinal contraction (DLC) during the postsystolic phase or by tissue synchronisation imaging (TSI) with a predefined time-difference in systolic maximal velocities”
“Most important, TSI appears to be a fast and reliable method to identify patients with intra-ventricular dyssynchrony likely to benefit from CRT.”
“Observational studies suggest that patients having more left ventricular dyssynchrony pre-implantation obtain greater benefit on ventricular function and symptoms with CRT.”
“Atrio-ventricular dyssynchrony (LVFT / RR) was defined as left ventricular filling time”
“Aim: To provide an analysis of the prevalence and type of dyssynchrony in patients included in the CARE-HF trial.”
“The use of device therapy (either ICD or CRT in combination with an ICD) aims to correct dyssynchrony and prevent sudden cardiac death.”
“Presented last year, the 12-month results from REVERSE provided some evidence suggesting that CRT benefited patients with ventricular dyssynchrony and the mildest forms of heart failure-that is, those who are asymptomatic as a result of therapy or are only mildly symptomatic. heartwire, the trial missed its primary end point, a clinical composite response that assessed worsening of heart failure through subjective and objective measures that included all-cause mortality, heart-failure hospitalizations, crossover due to worsening heart failure, NYHA class, and the patient global assessment.”
“LVFT / RR was present in 34\% and IVMD in 60\% of patients while intra-ventricular dyssynchrony was present in 85 \% (DLC) and 86 \% (TSI) with a high agreement between the measures (Kappascore”
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