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Examples

  • Stage 3: established end-organ damage like myocardial infarction, diabetic complications, severe osteoarthritis, significant psychopathology, significant functional limitations and impairment of well-being

    Dr. Sharma’s Obesity Notes » Blog Archive » Obesity Classification: Time to Move Beyond BMI? 2008

  • The review emphasized that end-organ vulnerability may be greatest in the fetus, and that for some chemicals the toxic effects seen in childhood are the result of continuous exposure beginning with conception.

    Dan Agin: Actualities: Weed Killers in Your Water 2009

  • Just when were you thinking about starting treatment on this guy anyways, AFTER end-organ damage?

    How Not to Treat Diabetes 1 Dinosaur 2008

  • In a short time, transplantation changed from an experimental oddity to a realistic option for end-organ failure.

    Analog Science Fiction and Fact 2004

  • The large medullated nerve fibers passing to the end-organ are from one to three or four in number; entering the fibrous capsule, they divide several times, and, losing their medullary sheaths, ultimately end in naked axis-cylinders encircling the intrafusal fibers by flattened expansions, or irregular ovoid or rounded disks (Fig. 939).

    X. The Organs of the Senses and the Common Integument. 1e. Peripheral Terminations of Nerves of General Sensations 1918

  • Soon after their emergence from the cord, these two nerves are wrapped together in the same sheath and proceed in this way to the periphery of the body, where the sensory nerve usually ends in a specialized _end-organ_ fitted to respond to some certain stimulus from the outside world.

    The Mind and Its Education George Herbert Betts 1901

  • At the same time the eye is appealed to by an infinite variety of stimuli in light, color, and objects; the skin responds to many contacts and temperatures; and every other type of end-organ of the body is acting as a "sender" to telegraph

    The Mind and Its Education George Herbert Betts 1901

  • _Pressure_ seems to have for its end-organ the _hair-bulbs_ of the skin; on hairless regions small bulbs called the _corpuscles of Meissner_ serve this purpose.

    The Mind and Its Education George Herbert Betts 1901

  • -- Thus it will be seen that in the simplest act which can be considered there are the following factors: (1) The stimulus which acts on the end-organ; (2) the ingoing current over an afferent nerve; (3) the sensory or interpreting cells;

    The Mind and Its Education George Herbert Betts 1901

  • Thus the eye is the end-organ of sight, and is a wonderfully complex arrangement of nerve structure combined with refracting media, and arranged to respond to the rapid ether waves of light.

    The Mind and Its Education George Herbert Betts 1901

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