from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A crystalline alkaloid, C33H35N5O5, derived from ergot that induces vasoconstriction and is used especially in treating migraine.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. An alkaloid, extracted from ergot, that causes constriction of blood vessels and has been used to treat migraine; it is related to lysergic acid.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. an alkaloid derived from ergot that is less toxic than ergot; causes constriction of blood vessels and is used to treat migraine
From the ninth to the 19th centuries, Europe suffered a succession of epidemics caused by contamination of rye with ergot, a poisonous mold that produces the potent toxin ergotamine, the consumption of which induces hallucinations, bizarre behavior, and violent muscle twitching.
If you read the link, you go on to discover that Ipomoea varieties contain a lot of ergotamine, which is a vasoconstrictor and uterine stimulator, and should be approached with caution.
Ergot, a fungus that grows largely on cereal grains, contains potent alkaloids such as ergotamine, which are key in synthesizing lysergic acid for use in popular hallucinogens.
It had a combination of all possible poisonous substances, major being "ergotamine", which is derived from the fungus infected "ergot of rye", which has the capacity to shrink blood vessels, technically known as vasoconstrictors.
Cafergot, a mixture of ergotamine tartrate and caffeine, is used to treat or prevent vascular headaches such as migraine and cluster headaches.
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From the ninth to the 19th centuries, Europe suffered a succession of epidemics caused by contamination of rye with ergot, a poisonous mold that produces the potent toxin ergotamine, consumption of which induces hallucinations, bizarre behavior and violent muscle twitching.
Do NOT use Clarithromycin if: you are allergic to any ingredient in Clarithromycin or any other macrolide (eg, erythromycin) you are taking cisapride, cyclosporine, dofetilide, eletriptan, ergot alkaloids (eg, ergotamine, dihydroergotamine), H
The women were challenged on moral grounds when in fact they had been poisoned by ergotamine contamination of rye.
I've had it for about 20 years; it's fairly common among people who get the kind of migraines I get, but it's also a fairly common (and permanent) sie effect of the medication that they used to use to treat/prevent migraines (ergotamine compounds, which I used to take tons of).
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