“Slide 11: Medications: Primary Agents Secondary Agents isoniazid* capreomycin ethambutol cycloserine pyrazinamide (PZA) ethionamide rifampin kanamycin Streptomycin para-aminosalicyclic acid (PSA) * most frequently used 01 / 01 / 09 11 www. healthnursesdoctors.com”
“Banerjee A, Dubnau E, Quemard A, Balasubramanian V, Um KS, et al. (1994) inhA, a gene encoding a target for isoniazid and ethionamide in”
“Mycolic acid biosynthesis is essential for mycobacterial survival and many antituberculosis drugs like isoniazid, ethionamide and thiolactomycin target enzymes of this exclusive pathway”
“Baulard AR, Betts JC, Engohang-Ndong J, Quan S, McAdam RA, et al. (2000) Activation of the pro-drug ethionamide is regulated in mycobacteria.”
“The preferred background regimen included kanamycin, ofloxacin, ethionamide, pyrazinamide, and cycloserine or terizidone, with modifications as needed according to susceptibility and side effects.”
“· history of allergy to ethionamide, isoniazid and nicotinamide.”
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