Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A vesicle responsible for the selective removal of plasma membrane proteins

Etymologies

Sorry, no etymologies found.

Examples

  • In their study, published in the Dec. 28 issue of Cell, the scientists zoomed in on a specific subclass of transcripts that are under the control of the exosome, a molecular machine in charge of controlled RNA degradation.

    2007 December - Telic Thoughts

  • ESI is focused on the development of exosome-targeted products and services that improve cancer diagnosis, provide post-treatment cancer surveillance, and aid in the discovery of biomarkers that allow doctors to optimize patient therapy.

    Aethlon Medical to Host Investor Event on January 20, 2011 - Yahoo! Finance

  • The resulting design provides us the novel ability to separate both exosome and viral targets away from blood cells so they can then be selectively and permanently removed from the circulatory system.

    Aethlon Medical to Host Investor Event on January 20, 2011 - Yahoo! Finance

  • They then fused the exosomes with targeting proteins from the rabies virus, which binds to acetylcholine receptors in brain cells, so the exosome would target the brain.

    BBC News - Home

  • Since the yield of exosomes by differential centrifugation can be increased by chemical reduction, Tamm-Horsfall protein may be a suitable normalizing variable for urinary exosome studies when quantitative urine collections are not practical.

    Naturejobs - All Jobs

  • This degradation pathway could involve the TRAMP complex and the exosome

    PLoS ONE Alerts: New Articles

  • Houseley J, Saveanu C, Petfalski E, Thompson E, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex.

    PLoS ONE Alerts: New Articles

  • High instability of a subset of lncRNAs both in yeast and mammals mainly depends on degradation by the nuclear exosome

    PLoS Biology: New Articles

  • Nielsen J, Kammler S, Lykke-Andersen S, Christensen M. S, et al. (2008) RNA exosome depletion reveals transcription upstream of active human promoters.

    PLoS Biology: New Articles

  • However, enhancer-generated transcripts are very unstable, possibly due to a constitutive surveillance by the nuclear exosome

    PLoS Biology: New Articles

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