- adj. biochemistry Of or relating to farnesol or its derivatives, especially to the metabolically active farnesyl pyrophosphate
“Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.”
“Giordano, Donatella Vizza, Salvatore Panza, Ines Barone, Daniela Bonofiglio, Suzanne A. Fuqua, Stefania Catalano and Sebastiano A.dò carried out the study, "A.tivated farnesoid X receptor inhibits growth of tamoxifen resistant breast cancer cells.”
“The study built on the recent discovery that farnesoid X receptor (FXR) - a nuclear receptor found mainly in the liver - is found in breast cancer tissue.”
“INT-747 is a novel derivative of a human bile acid CDCA (that binds to the farnesoid-X receptor).”
“INT-747 is a potent, first-in-class farnesoid X receptor (FXR) agonist derived from the primary human bile acid chenodeoxycholic acid (CDCA), the natural endogenous FXR agonist.”
“The farnesoid X receptor (FXR) is involved in regulation of bile acid and lipid metabolism.”
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