from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. One of the three enzymes in the prenyltransferase group, believed to play an important role in development of progeria and various cancers.
Tipifarnib is classified under drugs known as farnesyltransferase inhibitors (FTIs), which are being tested in people with myeloid leukemia, neurofibromatosis and other conditions.
Tipifarnib belongs to a class of drugs known as farnesyltransferase inhibitors (FTIs), which are being tested in people with myeloid leukemia, neurofibromatosis and other conditions.
In our experiments, inhibition of c-Ras by farnesyltransferase inhibitors and a dominant negative form of H-Ras (Ras S17N) suppressed muscle differentiation.
Salirasib is not a farnesyltransferase inhibitor (FTI) or Epidermal Growth Factor Receptor
The farnesyltransferase inhibitor (FTI) tipifarnib is effective in some patients with refractory or relapsed acute myeloid leukemia (AML), according to a report in the June 15th issue of Blood.
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