Definitions
Wiktionary
- n. One of the three enzymes in the prenyltransferase group, believed to play an important role in development of progeria and various cancers.
Etymologies
- farnesyl + transferase (Wiktionary)
Examples
“Tipifarnib is classified under drugs known as farnesyltransferase inhibitors (FTIs), which are being tested in people with myeloid leukemia, neurofibromatosis and other conditions.”
Anti-Cancer drug reverses fatal cardiovascular damage linked to progeria
“Tipifarnib belongs to a class of drugs known as farnesyltransferase inhibitors (FTIs), which are being tested in people with myeloid leukemia, neurofibromatosis and other conditions.”
“In our experiments, inhibition of c-Ras by farnesyltransferase inhibitors and a dominant negative form of H-Ras (Ras S17N) suppressed muscle differentiation.”
“Salirasib is not a farnesyltransferase inhibitor (FTI) or Epidermal Growth Factor Receptor”
“The farnesyltransferase inhibitor (FTI) tipifarnib is effective in some patients with refractory or relapsed acute myeloid leukemia (AML), according to a report in the June 15th issue of Blood.”
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