Century Dictionary and Cyclopedia
- n. A cell containing fat. See cut under sweat-gland.
“It is indeed widely believed that failure to accomodate excess calories in fat tissue (as a result of limited fat-cell formation) may promote fat deposition in other tissues (liver, muscle, heart), thereby promoting the development of metabolic risk factors like insulin resistance.”
“But fat-cell function doesn't necessarily correlate with weight gain.”
“The study found a hormonal cocktail routinely used in the lab induces a key genetic switch in the transition from fat-cell precursors to full-blown fat, researchers at University of Michigan Life Sciences Institute report in the September Cell Metabolism.”
“And yet, rid the fat-cell of the weight of his sordid gains, gaunt him down, as it were, like a hound for the wolf-trail, and he becomes at once an active and aggressive member of the binding-stuff group, ready for the repair of a wound or the barring out of a tubercle-bacillus.”
“When fat cells shrink, levels of a fat-cell hormone, leptin, drop faster than fat mass is reduced.”
“Our study highlights the fact that collagen VI, and possibly other extracellular matrix constituents, are extremely important in modulating fat-cell physiology," he said.”
“They even help fight wrinkles and may block fat-cell formation.”
“The amount of data is enormous, and may allow additional insights into how fat-cell genes are regulated.”
“New biocomputing methods allowed first author Martina I. Lefterova, a PhD candidate in the Lazar lab, to discover roughly 5,300 additional sites that PPAR gamma targets in fat-cell DNA.”
“Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has used state-of-the-art genetic technology to map thousands of positions where a molecular "master regulator" of fat-cell biology is nestled in DNA to control genes in these cells.”
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