Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • v. Simple past tense and past participle of flox.

Etymologies

Sorry, no etymologies found.

Examples

  • [22] to modify Wwox genomic sequences by flanking Wwox Exon 1 with two LoxP-recombination sites to generate a "floxed" -

    PLoS ONE Alerts: New Articles

  • When mice carrying such "floxed" genes are mated with transgenic mice expressing Cre recombinase, the target gene of the offspring is modified through Cre action [42-44].

    The 2007 Nobel Prize in Physiology or Medicine - Advanced Information

  • During the normal reverse transcription cycle of the virus before integration, the loxP sequence is duplicated into the 5 'LTR region, creating a loxP-flanked or' floxed 'version of the vector that integrates into the host chromosome.

    BioMed Central - Latest articles

  • 'floxed' STEMCCA vector in mouse iPSCs through adenoviral-mediated expression of Cre in the absence of selection

    BioMed Central - Latest articles

  • Expression of Cre and hence targeting of the floxed gene can be restricted to e.g. T cells (lck promoter), cardiac muscle (cardiac myosin promoter), neurons (enolase promoter) or epithelia (cytokeratin promoter).

    The 2007 Nobel Prize in Physiology or Medicine - Advanced Information

  • There are people in the U.S. which claim they have been “floxed”.

    Statin disaster | The Blog of Michael R. Eades, M.D.

  • Because the downstream neo gene used for selection could interfere with proper expression of the mutant protein, the floxed neo cassette was excised by crossing to the rosa26 Cre mice (Cre step in Fig. 1D).

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  • The function of Notch signaling during skin homeostasis was characterized using mice bearing homozygously floxed alleles for

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  • PCR products of 180 and 241 base pairs indicated the presence of the wild-type and floxed HNF4α alleles, respectively Total DNA and RNA were isolated from liver of HBV transgenic mice as described

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  • Mice were screened for the HBV transgene, the AlbCre transgene and the floxed HNF4α allele by polymerase chain reaction (PCR) analysis of tail DNA

    PLoS ONE Alerts: New Articles

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