“But nowadays these drugs are mainly used in combination products (Advair, Symbicort) that include inhaled corticosteroids such as fluticasone or budesonide, for which the risks -- if any -- are less clear.”
“Patents on several big name drugs, such as fluticasone propionate (Flonase), pravastatin”
“The basic treatment for asthma, which consists of administering weak doses of inhaled steroids such as fluticasone on a daily basis, has not proven to be effective in children with viral-induced asthma.”
“The new FDA restrictions apply to four drugs: salmeterol (Serevent) and formoterol (Foradil), which contain only an LABA, and the combination medications, salmeterol/fluticasone (Advair) and formoterol/budesonide (Symbicort), which contain both a LABA and an inhaled corticosteroid.”
“The new FDA restrictions apply to four drugs: salmeterol(Serevent) and formoterol (Foradil), which contain only an LABA, and the combination medications, salmeterol/fluticasone (Advair) and formoterol/budesonide (Symbicort), which contain both a LABA and an inhaled corticosteroid.”
“They include Adderall/Adderall XR (amphetamine/dextroamphetamine), Advair Diskus (fluticasone/salmeterol), Elidel (pimecrolimus), and Strattera (atomoxetine).”
“The recent well publicized TORCH trial compared salmeterol,fluticasone and the combination of the two and demonstrated fewer exacerbations with the combo treatment but did find more pneumonia in the group that received the ICS.”
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“The researchers used a family based model in which they studied the genetic makeup of children with asthma and their parents to identify genes that might play a role in response to inhaled steroids, such as AstraZeneca's budesonide sold under the Pulmicort brand and Glaxosmithkline's fluticasone or Flovent, a key ingredient in its Advair asthma treatment.”
“In this formulation fluticasone acts as an anti-inflammatory agent and salmeterol acts as a long-acting bronchodilator.”
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