function-associated

We have developed a novel immunoliposome method targeting the lymphocyte function-associated antigen-1 (LFA-1) integrin expressed on all leukocytes and evaluated it for systemic delivery of siRNA in a humanized mouse model.

Naturejobs - All Jobs Sang-Soo Kim 2010

SAR 1118 is a potent novel small molecule antagonist of lymphocyte function-associated antigen-1 (LFA-1; CD11a / CD18; aLß2) that can be targeted against a broad range of ocular inflammatory conditions including dry eye, allergies, uveitis, diabetic retinopathy and age-related macular degeneration.

GEN News Highlights 2009

Department of Chemistry and Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America T cells absorb nanometric membrane vesicles, prepared from plasma membrane of antigen presenting cells, via dual receptor/ligand interactions of T cell receptor (TCR) with cognate peptide/major histocompatibility complex (MHC) plus lymphocyte function-associated antigen 1

PLoS ONE Alerts: New Articles Kwangmi Kim et al. 2009

T cells absorb nanometric membrane vesicles, prepared from plasma membrane of antigen presenting cells, via dual receptor/ligand interactions of T cell receptor (TCR) with cognate peptide/major histocompatibility complex (MHC) plus lymphocyte function-associated antigen 1

PLoS ONE Alerts: New Articles Kwangmi Kim et al. 2009

Lymphocyte function-associated antigen 1 (LFA-1), a member of β2-integrin family, exerts multiple roles in host T cell immunity and has been identified as a useful drug-development target for inflammatory and autoimmune diseases.

Elites TV 2009