Century Dictionary and Cyclopedia
- n. A ferment which liquefies gelatin but which does not digest coagulated egg-albumin or fibrin in either acid, neutral, or alkaline solutions. It occurs widely distributed among bacteria, yeasts, molds, and in various phanerogams. According to recent research trypsin is not a unity, and a gelatinase has been demonstrated as one of its possible components.
“A novel diagnostic test to rapidly detect neutrophil gelatinase-associated lipocalin”
“Morrison CJ, Butler GS, Bigg HF, Roberts CR, Soloway PD, et al. (2001) Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway.”
“This compares favorably with other established biomarkers of AKI such as kidney injury molecule-1, neutrophil gelatinase-associated lipocalin,”
“These cells showed reduced migration and invasion that paralleled decreased gelatinase MMP-2 activity and increased expression and secretion of tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2.”
“The gelatinases comprise MMP-2 (gelatinase A) and MMP-9 (gelatinase B), both of which cleave several components of the extracellular matrix.”
“To identify factors that might predict response to sunitinib in patients with renal cell carcinoma, we measured serum vascular endothelial growth factor (VEGF) and neutrophil gelatinase-associated lipocalin (NGAL) levels.”
“The FDA has accepted for review a diagnostic test from Abbott Laboratories which can detect neutrophil gelatinase-associated lipocalin (NGAL), a biomarker which indicates that a patient is at risk for acute kidney injury (AKI).”
“Collagenase-1, stromelysin-1 and 92 kDa gelatinase are associated with tumor necrosis factor-alpha induced morphological change of human endothelial cells in vitro.”
“TNF-alpha and IL-1beta selectively induce expression of 92-kDa gelatinase by human macrophages.”
“Leppert D, Waubant E, Burk MR, Oksenberg JR, Hauser SL (1996) Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis.”
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