glucocerebrosidase love

glucocerebrosidase

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An enzyme that is needed to cleave, by hydrolysis, the beta-glucosidic linkage of glucocerebroside, an intermediate in glycolipid metabolism, and mutations in which cause Gaucher's disease.

Etymologies

Sorry, no etymologies found.

Examples

  • For example, people with Gaucher disease are deficient in the enzyme glucocerebrosidase, which is responsible for breaking down a certain fat molecule called glucocerebroside.

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  • Currently, several biotechnology companies have used plant biotechnology to produce protein pharmaceuticals, such as glucocerebrosidase to treat Gaucher disease in our case, lipase to treat cystic fibrosis, alpha-interferon, lactoferrin, and others, which are under evaluation in human studies

    PLoS ONE Alerts: New Articles

  • Taliglucerase alfa, the Company's proprietary plant-cell expressed form of glucocerebrosidase GCD, is in development for the treatment of Gaucher disease.

  • Thomas Goetz illustrates the utility of the 23andMe approach with a simple example: a massive study of the association between glucocerebrosidase mutations and Parkinson's disease published late last year, the key finding of which was successfully replicated by analysis done by 23andMe on their

    ScienceBlogs Channel : Life Science

  • The disorder is caused by lack of an enzyme called glucocerebrosidase.

    Medlogs - Recent stories

  • GBA gene which results in a deficiency of the lysosomal enzyme beta-glucocerebrosidase.

    RedOrbit News - Technology

  • The accumulation of glucocerebrosidase in the liver and spleen leads to organomegaly.

    RedOrbit News - Technology

  • The company's lead product is recombinant glucocerebrosidase, a treatment for Gaucher disease-a rare genetic disorder caused by a deficiency of the enzyme that breaks down fatty substances.

    News from The Scientist

  • In June 2009, Genzyme temporarily halted production of their modified glucocerebrosidase, Cerezyme, produced in mammalian cell cultures, due to viral contamination.

    News from The Scientist

  • Gaucher disease is an autosomal recessive disorder caused by mutations in the GBA gene which results in a deficiency of the lysosomal enzyme beta-glucocerebrosidase.

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