from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Excess sugar in the urine, often associated with diabetes mellitus.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The presence of sugars (especially glucose) in the blood, often as a result of diabetes mellitus
from the GNU version of the Collaborative International Dictionary of English
- n. Same as glucosuria.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. the presence of abnormally high levels of sugar in the urine
As a result of his work on the action of phlorhizin, a glucoside provoking glycosuria, and another one on nuclein metabolism in man, he was appointed
Macleod had, before this discovery, been interested in carbohydrate metabolism and especially in diabetes since 1905 and he had published some 37 papers on carbohydrate metabolism and 12 papers on experimentally produced glycosuria.
For the first time, therefore, an appearance of sugar in the urine - a glycosuria, though of a transitory nature - was experimentally produced; and consequently this discovery by Claude Bernard may be characterized as the starting-point of a series of experimental researches into the causes and nature of diabetes.
The attention of Claude Bernard was directed to this point, but he did not succeed in producing glycosuria by ligation of the duct which leads the secretion of the gland to the bowel or by injecting coagulating substances into it; the removal of the whole gland by operation he regarded as technically impracticable.
Best, and under my direction, he succeeded in 1922 in showing that such extracts reduced the hyperglycaemia and glycosuria in depancreatized dogs.
The addition of cane sugar, in amounts sufficient to cause a mild degree of glycosuria (50 to 100 g daily), had the immediate effect of preventing the loss of body weight, and in most animals, of causing it to become increased, especially when large amounts were given.
This was done by Banting in a severe case under the care of W.R. Campbell, with the result that the hyperglycaemia and glycosuria were diminished.
An increase in the dose previous to the appearance of glycosuria will prevent its occurrence.
Patients formerly considered bad surgical risks, if given proper dietetic treatment with insulin may be protected from the acidosis, hyperglycaemia, and glycosuria which otherwise usually result from the anaesthetic.
From a review of the work, Dr. Boyd has found that all the patients had had hyperglycaemia or even glycosuria at times, but if such occurrences were only transitory and infrequent, improvement in tolerance occurred.
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