glycyrrhizin

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“
TLR2-expressing 293 cells were incubated with the above stimuli in the presence or absence of glycyrrhizin (at a final concentration of 100 μM).

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Definitions (2)

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  1. A peculiar saccharine matter (C24H36O9) obtained from the root of Glycyrrhiza glabra.

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Examples (28)

  • The source of which comes from its active substance - glycyrrhizin - a very sweet glycoside occurring in the roots as the calcium plus potassium salts of glycyrrhizin acid. —  ConfectioneryNews RSS
  • The anti-viral herbal medicines Riyad uses include glycyrrhizin (licorice root powder), which induces the production of natural interferon, protects and heals the liver cells from damage, and also acts as an anti-allergic, anti-inflammatory and detoxifying element.
  • Specific activation of TLR2 signaling was induced by supernatants from Ad-TK (+GCV) - treated GBM cells; this activation was blocked by glycyrrhizin (a specific HMGB1 inhibitor) or with antibodies to HMGB1. —  PLoS Medicine: New Articles
  • Administration of either glycyrrhizin or anti-HMGB1 immunoglobulins to tumor-bearing Ad-Flt3L and Ad-TK treated mice, abolished therapeutic efficacy, highlighting the critical role played by HMGB1-mediated TLR2 signaling to elicit tumor regression. —  PLoS Medicine: New Articles
  • (HMGB1), a protein released by the dying tumor cells by showing that treatment of the tumor-bearing mice with the HMGB1 inhibitor glycyrrhizin blocked the therapeutic effect of Flt3L / TK expression. —  PLoS Medicine: New Articles
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