“In this environment, I began the transition to experimental molecular biology by using the heteroduplex method and electron microscopy to study the structure of plasmids of the sex factors and drug resistant factors of bacteria.”
“Ron Davis, a graduate student in Norman's lab at the time, had previously developed the heteroduplex method for visualizing deletions in phage genomes with the electron microscope.”
“EL, Herring B, Rodrigo AG, Mullins JI (1995) Genetic subtyping of human immunodeficiency virus using a heteroduplex mobility assay.”
“The melting curve analysis, determining the specificity of the reaction, was carried out immediately after the final PCR cycle by measuring the changes in fluorescence during slowly heating the amplicon/probe heteroduplex.”
“Detects mutations by enzymatic cleavage at mutation sites due to mutant: wild-type heteroduplex formation”
“As we proposed earlier, the left-handed filament represents a structural intermediate at the end of strand exchange reaction for ssDNA expulsion while holding onto a heteroduplex dsDNA.”
“SURVEYOR Scan technology is a novel approach to mutation detection that uses a PCR amplification reaction and hybridization to form heteroduplex DNA molecules in samples with K-RAS mutation.”
“New York: Alan R Liss Inc. Ronne H, Rothstein R (1988) Mitotic sectored colonies: evidence of heteroduplex DNA formation during direct repeat recombination.”
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