“Synosia brings a pipeline that includes two mid-stage drug candidates: one for Parkinson's disease, and a potential first-in-class hydroxyphenyl-pyruvate dioxygenase inhibitor intended for movement disorders.”
“Marchais-Oberwinkler S, Negri M, Kruchten P, Oster A, et al. (2009) New insights into the SAR and binding modes of bis (hydroxyphenyl) thiophenes and”
“Frotscher M, Ziegler E, Marchais-Oberwinkler S, Kruchten P, Neugebauer A, et al. (2008) Design, synthesis, and biological evaluation of (hydroxyphenyl) naphthalene and”
“Marchais-Oberwinkler S, Werth R, Negri M, Al-Soud YA, et al. (2008) Design, synthesis, biological evaluation and pharmacokinetics of bis (hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1).”
“For example, ferns and conifers have lignin composed mainly of p-hydroxyphenyl (H) and guaiacyl (G) lignin units.”
“Moench and the involvement of 1 - ACI - nitro-2 - (p-hydroxyphenyl) ethane as an intermediate.”
“)  P 4-hydroxymandelonitrile + NADP+ + H2 O Inhibitors 2-hydroxy (p-hydroxyphenyl) acetaldoxime”
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