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hyperproliferation

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An abnormally high rate of proliferation of cells by rapid division

Etymologies

hyper- +‎ proliferation (Wiktionary)

Examples

  • We've introduced genes that disrupt normal controls and drive the proliferation of the cell, and we've found several genes that cause hyperproliferation.

    Leading the Hunt For Cancer Genes

  • Postnatal K5-Cre ERT mediated inactivation of Notch1 in the skin results in hyperproliferation with expansion of the proliferative basal cell layer, hair loss and epidermal cyst formation within less then one month

    PLoS ONE Alerts: New Articles

  • This prompted us to investigate whether G-CSF might be responsible for the myeloid hyperproliferation.

    PLoS ONE Alerts: New Articles

  • There is no greater spur to hyperproliferation than the furling of the American nuclear umbrella.

    columbiatribune.com stories

  • Upon activation of PPARβ/δ, transgenic mice sustain an inflammatory skin disease strikingly similar to psoriasis, featuring hyperproliferation of keratinocytes, dendritic cell accumulation, and endothelial activation.

    PLoS ONE Alerts: New Articles

  • Moreover, Ki67 staining demonstrated massive hyperproliferation in the basal layer of the epidermis (fig. 3g).

    PLoS ONE Alerts: New Articles

  • Because missile defense is essential for protecting ourselves from the most menacing threat of the coming century -- nuclear hyperproliferation.

    StarTribune.com rss feed

  • Inv-Cldn6-CΔ187 transgenic mice overexpressing a cytoplasmic tail-ablated Cldn6 display epidermal hyperproliferation, apparently due to an inefficiency of Cldn protein membrane targeting, as a result of the unfolded protein response pathway

    PLoS ONE Alerts: New Articles

  • In contrast, apparently normal prenatal epidermal development and formation of a functioning EPB, but an abnormal postnatal lifelong keratinocyte hyperproliferation leading to progressive thickening of the epidermis - but no dermatitis, results when a mutant form of Cldn6 lacking its entire tail domain

    PLoS ONE Alerts: New Articles

  • Heath V, Suh HC, Holman M, Renn K, Gooya JM, et al. (2004) C/EBPalpha deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo.

    PLoS ONE Alerts: New Articles

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