Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biology An abnormally high rate of
proliferation ofcells by rapiddivision
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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We've introduced genes that disrupt normal controls and drive the proliferation of the cell, and we've found several genes that cause hyperproliferation.
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Postnatal K5-Cre ERT mediated inactivation of Notch1 in the skin results in hyperproliferation with expansion of the proliferative basal cell layer, hair loss and epidermal cyst formation within less then one month
PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010
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There is no greater spur to hyperproliferation than the furling of the American nuclear umbrella.
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Upon activation of PPARβ/δ, transgenic mice sustain an inflammatory skin disease strikingly similar to psoriasis, featuring hyperproliferation of keratinocytes, dendritic cell accumulation, and endothelial activation.
PLoS ONE Alerts: New Articles Malgorzata Romanowska et al. 2010
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Because missile defense is essential for protecting ourselves from the most menacing threat of the coming century -- nuclear hyperproliferation.
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Moreover, Ki67 staining demonstrated massive hyperproliferation in the basal layer of the epidermis (fig. 3g).
PLoS ONE Alerts: New Articles Malgorzata Romanowska et al. 2010
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This prompted us to investigate whether G-CSF might be responsible for the myeloid hyperproliferation.
PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010
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Upon activation of PPARβ/δ, transgenic mice sustain an inflammatory skin disease strikingly similar to psoriasis, featuring hyperproliferation of keratinocytes, dendritic cell accumulation, and endothelial activation.
PLoS ONE Alerts: New Articles Malgorzata Romanowska et al. 2010
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Inv-Cldn6-CΔ187 transgenic mice overexpressing a cytoplasmic tail-ablated Cldn6 display epidermal hyperproliferation, apparently due to an inefficiency of Cldn protein membrane targeting, as a result of the unfolded protein response pathway
PLoS ONE Alerts: New Articles Tammy-Claire Troy et al. 2009
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In contrast, apparently normal prenatal epidermal development and formation of a functioning EPB, but an abnormal postnatal lifelong keratinocyte hyperproliferation leading to progressive thickening of the epidermis - but no dermatitis, results when a mutant form of Cldn6 lacking its entire tail domain
PLoS ONE Alerts: New Articles Tammy-Claire Troy et al. 2009
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