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“That conclusion led Gao and Dang to suspect that some other mechanism was involved, such as a protein known to be dependent on free radicals called HIF-1 (hypoxia-induced factor), which was discovered over a decade ago by Hopkins researcher and co-author Gregg Semenza, M.D.,”
“If pressurized oxygen is administered within about one and a half minutes, a person in such a state is likely make a complete recovery with only minor injuries, though the hypoxia-induced blindness may not pass for some time.”
“He didn't think he quite liked that idea, and for a moment he let himself indulge in a fantasy that he hadn't died but was in the middle of a hypoxia-induced hallucination.”
“Bennewith KL, Nicolau M, Dornhofer N, Kong C, et al. (2006) Lysyl oxidase is essential for hypoxia-induced metastasis.”
“Second, this protein has also been reported to protect against hypoxia-induced apoptosis in hypoxia-induced apoptosis-resistant macrophages”
“In conclusion, our data suggest that hypoxia-induced edema formation is mediated by MMP-9-dependent TJ rearrangement by a mechanism involving VEGF.”
“Mechanistic studies suggest that hypoxia-induced PGC-1”
“Furthermore, suppression of Wnt4 expression in HypMSC, abrogated the hypoxia-induced vascular regenerative properties of these cells in the mouse hindlimb ischemia model.”
“As suggested by this study, this improved communication between ATP supply and demand pathways is likely a key strategy to limit hypoxia-induced energetic alterations.”
“During chronic hypoxia (CH), heart faces an increased workload as a result of the hypoxia-induced pulmonary hypertension under unfavorable conditions of decreased oxygen availability to oxidative cardiac metabolism.”
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