- adj. Within the epithelium
“In the other study, the drug was 78% effective against anal intraepithelial neoplasia, a precursor to anal cancer, associated with HPV in men ages 16 to 26 who have sex with men.”
“At the other end of the spectrum, some biopsies showed only occasional single intraepithelial polymorphs.”
“An interim analysis of vaccine trial data submitted to the FDA11 showed a disproportionate, but not statistically significant, number of cases of grade 2 or 3 cervical intraepithelial neoplasia related to nonvaccine HPV types among vaccinated women.”
“In the larger FUTURE II trial,6 rates of grade 2 or 3 cervical intraepithelial neoplasia or adenocarcinoma in situ were 1.3 in vaccinated women and 1.5 in unvaccinated women, an efficacy of 17%.”
“Findings from the FUTURE II trial showed that the contribution of nonvaccine HPV types to overall grade 2 or 3 cervical intraepithelial neoplasia or adenocarcinoma in situ was sizable.”
“In analyses by lesion type, the efficacy appears to be significant only for grade 2 cervical intraepithelial neoplasia; no efficacy was demonstrable for grade 3 cervical intraepithelial neoplasia or adenocarcinoma in situ.”
“Buried in the data of the report is the effectiveness of the vaccine in preventiong precancerous lesions called cervical intraepithelial neoplasia for any type of papilloma virus – only a 52% reduction overall.”
“Cervical dysplasia, cervical intraepithelial neoplasia (CIN), and squamous intraepithelial lesion (SIL) are all terms used to describe abnormal cells on or near the cervix.”
“This is termed the subepithelial plexus, and from it fibrils are given off which ramify between the epithelial cells, forming an intraepithelial plexus.”
“The growths, called vulvar intraepithelial neoplasia, or VIN, form on the external parts of the genital area, or vulva, including the labia and clitoris.”
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