Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A heavy drinker; an alcoholic.
  • noun One who regularly uses a steroid or other substance designed to enhance athletic performance.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun slang, dated An alcoholic.
  • noun slang A bodybuilder that uses, or appears to use, steroids and is of poor intellect or by extension any large male.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

From juice +‎ -head. Juice is a reference to protein shakes, anabolic steroids, and other performance enhancing drugs, many of which are taken in liquid form and called juice by analogy.

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