Definitions
Wiktionary
- n. Any of a set of peptidases, a subgroup of the serine protease family.
Examples
“The proposed treatment, ecallantide, is designed to partly block an enzyme known as kallikrein involved with the disorder.”
The Wall Street Journal: FDA Questions Effectiveness of Dyax Drug for Rare Disorder
“Aspirin interferes with chemical mediators of kallikrein system.”
“They believe plasma kallikrein slows clotting when there is lots of sugar in the blood, although the exact mechanism remains unclear.”
“The researchers found that a combination of high blood sugar and plasma kallikrein resulted in increased bleeding.”
“The group then studied the impact of a protein, plasma kallikrein, which had already been linked to sight problems in diabetics.”
“Further, Trasylol® was non-selective and inhibited many proteins in addition to plasmin, including Factor XIa and kallikrein, important regulators of the coagulation cascade.”
Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
“Omeros' agents are designed to selectively inhibit plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein, important regulators of the coagulation cascade.”
Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
“Omeros' proprietary antifibrinolytic agents are highly selective inhibitors of plasmin, the enzyme responsible for fibrinolysis and dissolving blood clots, while avoiding significant inhibition of Factor XIa and kallikrein.”
Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance
“Biomarkers such as IGF or kallikrein family members might improve sensitivity and specificity," he concludes.”
“KALBITOR is a plasma kallikrein inhibitor indicated for the treatment of acute attacks of hereditary angioedema (HAE) in patients 16 years of age and older.”
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