Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Of, pertaining to, or accompanied by lesions

Etymologies

Sorry, no etymologies found.

Examples

  • Early drafts of the Covenant contained the assumption that the socially unsane would naturally be hospitalized and readjusted, particularly since current psychiatry was quite competent to cure all non-lesional psychoses and cure or alleviate lesional psychoses, but Novak set his face against this.

    The Past Through Tomorrow

  • In the initial release, whole-skin expression profiles from paired lesional/non-lesional samples of

    PLoS ONE Alerts: New Articles

  • Hegmans JP, Croughs P, Troost RJ, Prins JB, et al. (1997) The IL-1 system in psoriatic skin: IL-1 antagonist sphere of influence in lesional psoriatic epidermis.

    PLoS ONE Alerts: New Articles

  • Geneset Enrichment analysis (GSEA) independently confirmed a highly significant enrichment of those genes upregulated in psoriasis (defined as gene-set) in lesional skin of PPARβ/δ mice (figure 5c).

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  • In order to independently confirm those results, we re-analyzed two publicly available large gene expression datasets, totalling 58 paired lesional and non-lesional skin samples, for the expression of all PPAR isotypes.

    PLoS ONE Alerts: New Articles

  • Upregulation of psoriasis-associated genes in lesional skin of PPARβ/δ transgenic mice.

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  • FC = fold change lesional vs. non-lesional (psoriasis), or induced vs. non-induced (PPARβ/δ transgenic mice).

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  • As shown in figure 5a, most of the top 50 genes upregulated in lesional skin of PPARβ/δ mice were found congruently upregulated in human psoriasis.

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  • Representative immunohistochemistry of paraffin-embedded lesional (left) and control (middle) skin samples stained with anti-PPARβ/δ, as well as staining control (right).

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  • Westergaard M, Henningsen J, Johansen C, Rasmussen S, Svendsen ML, et al. (2003) Expression and localization of peroxisome proliferator-activated receptors and nuclear factor kappaB in normal and lesional psoriatic skin.

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