mRNA

• “The genetic code in mRNA is described as being the 'sense' sequence, and injecting 'antisense' RNA, which can pair with the mRNA, also had no effect.”

  Press Release: The 2006 Nobel Prize in Physiology or Medicine

• “Despite its importance, relatively little is known about the structural determinants of beta-globin mRNA stability or how they contribute to regulating beta-globin gene expression.”

  Sickle cell disease research at The Children's Hospital

• “And there is excellent evidence in mRNA assays that modern humans didn't come about as mutated Neandertals … they didn't father (or, more pertinently, mother) us.”

  Amazing Brain Evolution

• “In 1998, the American scientists Andrew Fire and Craig Mello published their discovery of a mechanism that can degrade mRNA from a specific gene.”

  Press Release: The 2006 Nobel Prize in Physiology or Medicine

• “However, in a follow-up study published in PNAS the same year, Fire provided good evidence for the view that mRNA is the target for dsRNA (recognition via complementary strands), and that the targeted mRNA is degraded prior to translation, i.e. dsRNA exerts its effect at the posttranscriptional level26.”

  Advanced Information: The 2006 Nobel Prize in Physiology or Medicine

• “The effect on mex-3 mRNA content in embryos after injection of single-stranded or double-stranded mex-3 RNA into the gonad of C.elegans. mex-3 mRNA is abundant in the gonads and early embryos.”

  Advanced Information: The 2006 Nobel Prize in Physiology or Medicine

• “The RISC complex cuts the mRNA strand, and the mRNA is subsequently degraded.”

  Advanced Information: The 2006 Nobel Prize in Physiology or Medicine

• “This stimulated our interest in comparing the relative structures of nuclear precursor RNA and cytoplasmic mRNA from the adenovirus genome.”

  Phillip A. Sharp - Autobiography

• “This project is designed to establish a comprehensive understanding of the structures, factors and mechanisms that affect the stability of human beta-globin mRNA. This information promises to be helpful in designing therapies for sickle cell disease.”

  Sickle cell disease research at The Children's Hospital

• “It makes single-stranded copies of DNA's genes, called mRNA, which tell the cell to produce proteins.”

  BigHominid's Hairy Chasms

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