Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun medicine An anti-addictive
drug , anamino derivative ofnorbornane , used as anicotine antagonist
Etymologies
Sorry, no etymologies found.
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Examples
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Researchers at the University of South Florida later began testing mecamylamine in the hope it would help children with Tourette's syndrome.
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TC-5214 is a tweaked version of mecamylamine, a drug introduced in the 1950s to treat high blood pressure.
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Researchers at the Wilmer Eye Institute of Johns Hopkins University School of Medicine in Maryland completed a multicenter human clinical trial treating diabetic macular edema with mecamylamine, a topical drug developed by the South San Francisco biotech company CoMentis,
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In the Johns Hopkins study, participants with diabetic macular edema were asked to give themselves mecamylamine eye drops twice a day for 16 weeks.
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(Preclinical research with diabetic mice showed that mecamylamine had the ability to stop the process that contributed to the development and progression of diabetic macular edema.)
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The dose of mecamylamine was escalated over the two cycles from the lower dose in the first cycle to the higher dose in the second cycle.
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AGI-004 is a once-daily controlled release transdermal patch containing the nicotinic antagonist mecamylamine.
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These mice also had high cortisol levels in their blood and tissues, and mecamylamine blocked this effect.
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AGI-004 is a once-daily controlled release transdermal patch containing the nicotinic antagonist mecamylamine.
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Notes to Editors: About AGI-004 and chemotherapy-induced diarrheoa (CID) AGI-004, a controlled release form of mecamylamine, is a potent, non-competitive specific antagonist at nicotinic acetylcholine receptors (nAChR).
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