Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- n. A large bone marrow cell with a lobulate nucleus that gives rise to blood platelets.
Wiktionary
- n. anatomy A large cell, found in bone marrow, responsible for the production of platelets.
GNU Webster's 1913
- n. (Anat.) A large bone marrow cell not usually found in the circulating blood; it is regarded as the precursors of blood platelets; it is up to 100 μm in diameter, with a polyploid nucleus. Also referred to as
megacaryocyte ,megalokaryocyte , andthromboblast .
WordNet 3.0
- n. a large bone marrow cell; regarded as the source of blood platelets
Etymologies
- From mega- + karyocyte (Wiktionary)
Examples
“Platelets are formed in the cytoplasm of a very large cell, the megakaryocyte.”
“The cytoplasm of the megakaryocyte fragments at the edge of the cell.”
“The condition also is characterized by proteolysis of platelet α-proteins such as platelet factor V and von Willebrand factor, further interfering with clot function, and with increased uPA messenger RNA levels, particularly during megakaryocyte differentiation.”
“Our study indicates that the dysregulation of PLAU in Quebec platelet disorder extends beyond megakaryocyte lineage, to involve other cells of the myeloid lineage," the investigator said.”
“Lagrue-Lak-Hal AH, Debili N, Kingbury G, Lecut C, Le Couedic JP, et al. (2001) Expression and function of the collagen receptor GPVI during megakaryocyte maturation.”
“Boer AK, Los EL, Esselink MT, Vellenga E (2005) Stem cell factor synergistically enhances thrombopoietin-induced STAT5 signaling in megakaryocyte progenitors through JAK2 and Src kinase.”
“EPO - and SCF-induced STAT5 phosphorylation was largely restricted to the megakaryocyte-erythroid progenitor (MEP) compartment, while G-CSF as well IL-3 and GM-CSF were most efficient in inducing STAT5 phosphorylation in the myeloid progenitor compartments.”
“TPO influences megakaryocyte (MK) development by controlling proliferation, differentiation, survival and endoduplication”
“Hundred thousand 105 whole BM cells were assessed for megakaryocyte progenitor activity in a CFU-Mk assay, MegaCult-C (Stem cell Technologies, Vancouver, CA) per the manufacturer's instructions.”
“We hypothesize that SHIP might control megakaryocytopoiesis through effects on proliferation of megakaryocyte progenitors (MKP) and megakaryocytes (MK).”
Lists
These user-created lists contain the word ‘megakaryocyte’.
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sionnach's Words
contumely, fomite, holmgang, poltroon, eleemosynary, obsidian, nugatory, grindcore, felch, recrudescent, pyx, parenteral and 3271 more...
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Blood Line
Blood-related words.
neutrophil, platelet, erythrocyte, leucocyte, waldenstrom's mac..., megakaryocyte, monoclonal gammop..., pernicious anaemia, megaloblast, thalassaemia, phagocyte, basophil and 5 more...
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