Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Describing a neurotransmitter or cell receptor whose action is mediated by metabolic functions (e.g. enzyme activation)

Etymologies

Sorry, no etymologies found.

Examples

  • LY2140023 is designed to stimulate substances in the brain known as metabotropic glutamate receptors, or mGlu for short.

    Lilly Tests New Schizophrenia Drug

  • This is particularly true of a subset of slow-acting glutamate receptors called metabotropic receptors, which have a more limited distribution in the nervous system and which are only engaged by particular patterns of neural activity.

    Forbes.com: News

  • One receptor, called the metabotropic glutamate receptor type 5 mGluR5, has received particular attention, as it is strongly expressed in key portions of the brain's pleasure circuit.

    Forbes.com: News

  • The proprietary molecule specifically inhibits a receptor subtype called the metabotropic glutamate receptor 2 (mGluR2) via negative allosteric modulation (NAM).

    WebWire | Recent Headlines

  • The new study found rapid-fire inputs less than a second long initiate a cellular memory process in single cells lasting as long as minute, a process called metabotropic glutamate transmission.

    WHAT REALLY HAPPENED

  • The researchers found that rapid-fire inputs less than a second long initiate a cellular memory process in single cells lasting as long as minute, a process called metabotropic glutamate transmission.

    Nano Tech Wire

  • ADX10059 is an allosteric inhibitor - a negative allosteric modulator (NAM) - of a glutamate receptor subtype called metabotropic glutamate receptor 5 (mGluR5).

    Marketwire - Breaking News Releases

  • In the late 1980s, Bear's research suggested that a cell receptor - called a metabotropic glutamate receptor - plays a critical role in synaptic plasticity.

    PhysOrg.com - latest science and technology news stories

  • "Addex has made exceptional progress in the area of mGlu -- metabotropic glutamate -- receptor allosteric modulation," said Darryle Schoepp, senior vice president and franchise head of Neuroscience at Merck Research Laboratories.

    Addex and Merck to Collaborate

  • Addex, founded in 2002, is also in collaboration with Ortho-McNeil, a company belonging to Johnson & Johnson of the U.S., to develop a different metabotropic glutamate receptor for conditions that could include schizophrenia and anxiety.

    Addex and Merck to Collaborate

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