Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of several
enzymes thatcatalyze methylation , especially ofnucleic acids
Etymologies
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Examples
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Maybe the demethylation is due to cumulative damage to the DNA itself, maybe the methylase enzyme becomes less active in the course of time, maybe something else.
The Boat of a Million Years Anderson, Poul, 1926- 1989
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It appears to mediate epigenetic changes introduced through methylation of DNA by binding the methylase PRC2 (Polycomb Repressive Complex 2) to the
Social Security Reports, News and Informaion MedPageToday.com - medical news plus CME for physi 2010
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Using a modified DNA methylase accessibility assay, they could distinguish between different levels of chromatin structures associated with distinct histone modification patterns.
PhysOrg.com - latest science and technology news stories 2010
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Although a direct molecular mechanism to explain these observations is still lacking, basic mechanisms by which DNA methyl-transferases and putative DNA de-methylase complexes function have recently been uncovered
PLoS ONE Alerts: New Articles Mehregan Movassagh et al. 2010
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COMPASS was the first H3K4 methylase to be identified, and human MLL is also found in COMPASS-like complexes capable of methylating H3K4, a posttranslational modification marking chromosomes for transcription.
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MLL2, on the other hand, is another methylase that activates gene expression.
unknown title 2009
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EZH2 is a methylase enzyme that modifies a specific lysine residue on histone H3, associated with gene repression.
unknown title 2009
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These specific inhibitors are of great importance as plant growth reg - ulators, fungicides and herbicides in the agricultural and medical fields [1,2,7,12]; target enzyme for the design of phyla-specific sterol 14a-de - methylase inhibitors all known functional sterols lack a 14a-methyl group, and therefore the
Recently Uploaded Slideshows arab2000.forumpro.fr@slideshare.net(arab2000.forum 2009
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Growth of the C. trachomatis ksgA mutant was negatively affected in cell culture highlighting the importance of the methylase in the development of these obligate intracellular and as yet genetically intractable pathogens.
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