Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics The set of
nucleic acid methylation modifications in an organism'sgenome or in a particularcell
Etymologies
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Examples
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Rakyan VK, Turner DJ, Flicek P, Li H, et al. (2008) A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis.
PLoS ONE Alerts: New Articles Mehregan Movassagh et al. 2010
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Irizarry RA, Ladd-Acosta C, Wen B, Wu Z, Montano C, et al. (2009) The human colon cancer methylome shows similar hypo - and hypermethylation at conserved tissue-specific CpG island shores.
PLoS ONE Alerts: New Articles Mehregan Movassagh et al. 2010
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The projects apply these methods to define the role of the methylome in generating heritable variation in human evolution, the nature of dynamic changes in the methylome during human aging, and the role of short RNAs in establishing genomewide methylation patterns.
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"I expect the cost of a similar methylome will fall to $10,000 in the next six months," he says.
Scientific American 2010
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More information: The research findings are published in the Feb. 4, 2010 online issue of Genome Research under the title, "Dynamic changes in the human methylome during differentiation."
PhysOrg.com - latest science and technology news stories 2010
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- Analysis of methylome and miRNA data by developing and applying bioinformatic methods for the analysis of bisulfite sequencing data and miRNA profiling
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MEMS metagenomics metamaterials metananocircuitry methane methuselarity methylome mexico mice microbiome microcontact printing micronutrient
Next Big Future 2009
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- Analysis of methylome and miRNA data by developing and applying bioinformatic methods for the analysis of bisulfite sequencing data and miRNA profiling
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Rauch TA, Wu X, Zhong X, Riggs AD, Pfeifer GP (2009) A human B cell methylome at 100-base pair resolution.
PLoS ONE Alerts: New Articles Mehregan Movassagh et al. 2010
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With these comprehensive DNA methylome maps, scientists now have a blueprint of key epigenetic signatures associated with differentiation. "
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