monoallelic

Three of the affected females had a monoallelic homozygous mutation, four had heterologous or mosaicism biallelic mutations, and the remainder had three different mosaic mutations.

PLoS ONE Alerts: New Articles Tomoji Mashimo et al. 2010

To understand some of the mechanisms involved, we examined the role of monoallelic loss or Atm and Brca1 on cell transformation and apoptosis induced by radiation.

BioMed Central - Latest articles Fengtao Su 2010

In index cases from 1,100 German families with gynecological malignancies, we identified six monoallelic pathogenic mutations in

Naturejobs - All Jobs Alfons Meindl 2010

In order to avoid null alleles, datasets in which one of the homozygotes gave a steady state level was set equal to zero if the sum of the monoallelic phenotypes differed less than 5% from the biallelic phenotype.

PLoS ONE Alerts: New Articles Arne B. Gjuvsland et al. 2010

For each parameter set a random initial condition was chosen, and the biallelic and monoallelic equations were integrated numerically until a stable state was reached.

PLoS ONE Alerts: New Articles Arne B. Gjuvsland et al. 2010

To understand some of the mechanisms involved, we examined the role of monoallelic loss or Atm and Brca1 on cell transformation and apoptosis induced by radiation.

BioMed Central - Latest articles Fengtao Su 2010

RAD51C in a Fanconi anemia-like disorder, while a second study reports monoallelic mutations in the same gene associated with increased breast cancer …

Naturejobs - All Jobs Fiona Vaz 2010

PTPN2 in individuals 1 to 7, and monoallelic deletion of

Naturejobs - All Jobs Maria Kleppe 2010

The classical concepts of dominant or additive gene actions do not follow from whether the monoallelic contributions of the two different alleles in the heterozygote act in an additive way or not, but are given by a specific relationship between the degree of allele interaction for all the three genotypes.

PLoS ONE Alerts: New Articles Arne B. Gjuvsland et al. 2010

Furthermore, the occurrence of monoallelic maternal expression of STAT5A was significantly higher in blastocysts, while paternal expression was more frequent in degenerative embryos.

BioMed Central - Latest articles 2009