Definitions
Wiktionary
- n. genetics Any substance used to modify gene expression
Examples
“Finally, the control morpholino, which is a five base mismatch of the original MO, did not result in any phenotype, apoptosis or upregulation of the p53 pathway (”
“AVI's proprietary, intrinsically charge-neutral, phosphorodiamidate morpholino oligomer PMO”
“AVI BioPharma is focused on the discovery and development of RNA-based drugs utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.”
“RNA and morpholino antisense oligonucleotides were microinjected into the yolk of one-cell stage embryos.”
“Upon the introduction of an antisense morpholino (2 mM) against granzyme G to knock-down endogenous gene function, all embryos were arrested at the 2 - to 4-cell stages of egg cleavage, and the de novo synthesis of zygotic RNAs was decreased.”
“Using a PDGFR tyrosine kinase inhibitor, a morpholino oligonucleotide specific to”
“AVI BioPharma is focused on the discovery and development of RNA-based therapeutics utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.”
“AVI BioPharma is focused on the discovery and development of RNA-based medicines utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.”
“Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists first performed a series of studies with mouse and guinea pig models of Ebola to screen various chemical variations.”
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