American Heritage® Dictionary of the English Language, Fourth Edition
- n. Any of a group of vertebrate oncogenes whose product, a DNA binding protein, is thought to promote the growth of tumor cells.
- Possibly from my(elo)c(ytomatosis virus). (American Heritage® Dictionary of the English Language, Fourth Edition)
“For example, in cancer that had spread from the pancreas to the lung, Campbell found that a gene called myc had been mutated.”
“Furthermore, leukemic malignancies were forced through integration of fusion-genes that mimic chromosomal alterations, such as myc-IgH”
“This man who got this country into so myc debt and other troubles wants the AMericans to give credit to ANYTHING he has to say?”
“It is possible now to produce a stem cell from almost any other human cell instead of using embryos as needed previously, albeit the risk of tumorigenesis due to c-myc and retroviral gene transfer remains to be determined.”
“Even so, as in myc constituency it's simplay Labour or Conservative, I'll vote Conservative.”
“To test the roles of other oncogenes and environmental stimuli, Leder created a second OncoMouse, in which two activated proto-oncogenes, ras and myc, were engineered into the chromosome and expressed in breast cells.”
“Many of the genes and pathways that enabled each of these six behaviors had concretely been identified—ras, myc, Rb, to name just a few.”
“The mouse embodied the maturity of cancer genetics: scientists had created real, living tumors not just abstract, etiolated foci in petri dishes by artificially manipulating two genes, ras and myc, in an animal.”
“Rapid cellular proliferation, or the insensitivity to growth-arresting signals, or tumor angiogenesis, can all largely be explained by aberrantly activated and inactivated pathways such as ras, Rb, or myc in cancer cells.”
“If myc was permanently activated in the embryo, the embryo turned into a ball of overproliferating cells, then involuted and died through unknown mechanisms.”
Looking for tweets for myc.