from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Prolonged abnormal dilatation of the pupil of the eye caused by disease or a drug.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The condition of having abnormally large and dilated pupils due to disease or drugs, particularly stimulants such as (meth)amphetamines, cocaine, etc.
from the GNU version of the Collaborative International Dictionary of English
- n. A long-continued or excessive dilatation of the pupil of the eye.
from The Century Dictionary and Cyclopedia
- n. In medicine, a morbid dilatation of the pupil of the eye.
- n. Hydrophthalmia.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. reflex pupillary dilation as a muscle pulls the iris outward; occurs in response to a decrease in light or certain drugs
Today I learned that cats exposed to atropine, or plants containing atropine-like substances, can cause mydriasis that persists for 4 weeks or more, as evidenced by my seemingly possessed cat who may have ingested chili peppers weird cat or petunias.
OMS302, one of Omeros' proprietary PharmacoSurgery™ products, is added to standard irrigation solution used during cataract and other lens replacement surgery to maintain intraoperative mydriasis pupil dilation and reduce postoperative pain and inflammation.
The co-primary endpoints for these trials - maintenance of intraoperative pupil dilation mydriasis and reduction of postoperative pain - are the same as those achieved in the recently completed 221-patient Phase 2b trial.
OMS302 is a proprietary combination of an anti-inflammatory active pharmaceutical ingredient (API) and an API that causes mydriasis (pupil dilation), each with well-known safety and pharmacologic profiles.
In a 221-subject Phase 2b clinical trial that evaluated OMS302 in patients undergoing cataract surgery, OMS302 demonstrated clinically meaningful and statistically significant benefits in both prespecified co-primary endpoints - maintenance of intraoperative mydriasis and reduction of pain in the early postoperative period.
OMS302 will be evaluated in both refractive lens exchange and cataract surgery patients for maintenance of intraoperative mydriasis and reduction of postoperative pain.
The drug information clearinghouse Erowid - not known for anti-drug polemics by any stretch - has this to say about Jimson weed intoxication: Symptoms include mydriasis; cycloplegia; flushed, warm, dry skin; dry mouth; ileus; urinary retention; tachycardia; hyper or hypotension; delirium with hallucinations; jerky, myoclonic movements; choreoathetosis; hyperthermia; coma; respiratory arrest; rare seizures; and central stimulation followed by depression.
Sympathomimetic effects - mydriasis, BP, HR, skin pallor.
The ICP oculomotor nerve lesion (and ipsilateral mydriasis), psychic monitoring catheter can be made of optic fiber, polyethylene blunting, behavioral changes and convulsion. 1,2,3 or silicon, and has greater advantages when inserted in the During the unbalance phase, conscience level and ventricles, what allows it to drain CSF.
Bilateral mydriasis is serious and vomiting and papilar edema, which are not always present at mostly shows an irreversible lesion. 2,4,5 the same time.
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