from The American Heritage® Dictionary of the English Language, 4th Edition
- n. An undifferentiated cell in the mesoderm of the vertebrate embryo that is a precursor of a muscle cell.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. an undifferentiated stem cell that develops into muscle tissue
from The Century Dictionary and Cyclopedia
- n. A cell which gives rise to muscular fibers; the formative cell-element of muscular tissue.
Put simply, the process relies on a muscle precursor cell known as a myoblast, a sort of stem cell preprogrammed to grow into muscle.
In this study, we show that Pitx2 is phosphorylated by the protein kinase Akt2 and is necessary to ensure proper C2C12 myoblast proliferation and differentiation.
We propose that unphosphorylated Pitx2 is required to favor HuR-mediated Ccnd1 mRNA stabilization, thus sustaining myoblast proliferation.
Then chanteuse Susan Marder, the show's science jingle writer, belted out an ode to the joys of consuming test-tube generated faux meat: "Give it to the kids at every seating/myoblast is what you're eating!"
Langley B, Berry C, Sharma M, Kirk S, et al. (2000) Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation.
Myostatin is a member of the transforming growth factor-beta (TGF-β) superfamily of growth and differentiation factors and is a primary regulator of muscle growth both pre - and postnatally, primarily via inhibition of myoblast proliferation and differentiation
Langley B, Thomas M, Bishop A, Sharma M, Gilmour S, et al. (2002) Myostatin inhibits myoblast differentiation by down-regulating MyoD expression.
Bernardi H, Garandel V, Rabenoelina F, Vernus B, et al. (2003) Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin.
The medium was changed after 6 h and replaced with myoblast complete growth medium.
Primary myoblasts were seeded at 15,000 cells per well in myoblast complete growth medium.
Wordnik is becoming a not-for-profit! Read our announcement here.