from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The univalent radical derived from myristic acid by loss of the hydroxy group
Wyatt said his team had discovered a compound that disrupts an enzyme called N-myristoyl transferase, or NMT, which is essential for the survival and growth of the parasites injected into the victim by the tsetse fly's bite.
Mutagenesis studies indicated a requirement for serine five residues from the amino terminus, reminiscent of myristoyl transferase, but not of ghrelin acylation.
We obtained a sample of N-myristoyl transferase from Drs. K.E. Seaton and C.D. Smith, used it as the enzyme source in our standard assay, and confirmed the total lack of effect of zinc on N-myristoyl transferase octanoic acid transfer (
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